(Download) "Down Syndrome with Myelodysplasia of Megakaryoblastic Lineage (Research AND REPORTS)" by Clinical Laboratory Science # eBook PDF Kindle ePub Free
eBook details
- Title: Down Syndrome with Myelodysplasia of Megakaryoblastic Lineage (Research AND REPORTS)
- Author : Clinical Laboratory Science
- Release Date : January 22, 2006
- Genre: Engineering,Books,Professional & Technical,
- Pages : * pages
- Size : 183 KB
Description
The association between Down syndrome and acute myelogenous leukemia (AML) has been well documented. (1,2,3) AML in Down syndrome is usually a specific type of megakaryoblastic leukemia (M7, AMKL). (1) A myelodysplastic syndrome generally precedes this malignancy. Down syndrome patients with AMKL have a much better prognosis than other children with AML. (5) A case study of a 22-month-old female with Down syndrome and myelodysplastic syndrome of a megakaryoblastic lineage is presented here. Upon admission to a pediatric hematology/ oncology clinic, flow cytometry results reported a distinct population of phenotypically abnormal myeloblasts expressing myeloid antigens and the immature cell markers.
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